- Anatomy [A]
- Organisms [B]
- Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E] - Psychiatry and Psychology [F] - Disciplines and Occupations [H] - Anthropology, Education, Sociology, and Social Phenomena [I] - Technology, Industry, and Agriculture [J] - Brain related traits [aggregated from above]
Key
Description
Category
MeSH category of trait (CAUSALdb)
Sample size
number of samples
Author
first author of paper
PMID
PubMed id
Year
year published
Gene
ENSEMBL id
Symbol
HUGO gene symbol
Variant
variant identifier
GWAS prob
posterior probability from fine mapping GWAS (CAUSALdb)
eQTL prob
posterior probability from fine mapping GWAS (eQTL meta-analysis)
Shared causal prob
product of GWAS prob and eQTL prob. Click to see plots
Shared prob
sum of shared causal probabilities, summed over all variants for tis gene-trait pair. A high probability indicates that the GWAS and eQTL signals co-localize, even if the candidate causal set is large.
Order
1) primary eQTL, 2) secondary eQTL conditioned on the top association from the primary analysis, 3) tertiary, conditioned on top primary and secondary associations, etc.
Cell type
indicates if gene is a marker gene for a particular cell type based on single cell RNA-seq from Lake, Darmanis and Habib.